Published in TB and Outbreaks Week, March 8th, 1999
Standard chemotherapy for tuberculosis (TB) in children uses hepatotoxic drugs. Published data and guidelines on the monitoring of liver function during TB treatment are often contradictory and not directly relevant to the pediatric population.
In this study, D. Corrigan and J. Paton of Glasgow's Royal Hospital for Sick Children monitored 43 children (median age = 6.6 years, 0.7-15.1; 49 percent male; 72 percent Caucasian) being treated for TB infection (n = 8) or disease (n = 35) with triple therapy, using...
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