"INH Prophylaxis Antepartum vs Postpartum in Women with a Positive Tuberculin Skin Test: Results of a Decision Analysis Model."

According to an abstract submitted by the authors to the 36th Annual Meeting of the Infectious Diseases Society of America, held November 12-15, 1998, in Denver, Colorado, "Objective: Compare costs and risks of Antepartum (AP) vs postpartum (PP) isoniazid (INH) TB prophylaxis in pregnant women {{<=}}35 yrs with a positive PPD skin test and no active disease. Methods: We used a decision analysis model and a health care system perspective to compare health outcomes and costs of INH prophylaxis during pregnancy vs delaying prophylaxis, as per ATS/CDC guidelines, until postpartum. Outcomes included active TB, INH-induced hepatitis, and life expectancy. Probabilities and...

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