Therapy

Hemodialysis Doesn't Affect TB Treatment

Published in TB and Outbreaks Week, May 31st, 1999

Hemodialysis has little effect on the efficacy of first line tuberculosis agents, according to a report from Colorado's National Jewish Medical and Research Center.

This study examined hemodialysis clearances of isoniazid (INH), rifampin (RIF), pyrazinamide (PZA), and ethambutol (EMB) ("The Effect of Hemodialysis on Isoniazid, Rifampin, Pyrazinamide, and Ethambutol," American Journal of Respiratory and Critical Care Medicine, May 1999;159(5):1580-1584).

Seven chronic hemodialysis patients were studied. Six were given single oral doses (INH 300 mg, RIF 600 mg, PZA 1,000 mg, and EMB 25 mg/kg) two hours before hemodialysis (Cobe Centrysystem 3...

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Source: TB and Outbreaks Week (1999-05-31)

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