Mycobacterium tuberculosis (Virulence)
"Enhanced Capacity of a Widespread Strain of Mycobacterium tuberculosis To Grow in Human Macrophages."
Published in TB and Outbreaks Week, June 14th, 1999
According to the authors' abstract of an article published in Journal of Infectious Diseases, "To determine whether the extent of spread of Mycobacterium tuberculosis strains in the community correlated with their capacity to replicate in human macrophages, intracellular growth rates of M. tuberculosis patient isolates were measured. Strain 210 caused disease in 43 patients in central Los Angeles [California USA], 3 'small-cluster' strains caused disease in 8-23 patients, and 5 'unique' strains each caused disease in only 1 patient who was positive by sputum acid-fast smear and spent substantial amounts of time at homeless shelters that were tuberculosis transmission sites. ...
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