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Influenza Vaccine

"Paradoxical Response to a Novel Influenza Virus Vaccine Strain: The Effect of Prior Immunization."

Published in TB and Outbreaks Week, June 28th, 1999

According to the authors' abstract of an article published in Vaccine, "Background: Repeated influenza immunization does not appear to adversely affect the serum antibody response to new influenza strains. Objective: To determine whether the immune response to a new influenza strain was inferior in persons previously vaccinated compared with persons not previously vaccinated. Design: Randomized, double-blind clinical trial. Setting: University-affiliated community teaching hospital. Patients: 139 healthy adult men and women, mean age 38 years. Intervention: Subjects were vaccinated as part of another study. They received influenza...

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