Immunology

TB Isolate Isn't Hypervirulent

Published in TB and Outbreaks Week, July 26th, 1999

The isolate Mycobacterium tuberculosis CDC1551 does not appear to be hypervirulent, as previous reports have claimed, but does promote a more vigorous host response.

In this study, researcher C. Manca and colleagues from New York's Rockefeller University and the U.S. National Institutes of Health examined M. tuberculosis CDC1551, a clinical isolate reported to be hypervirulent and to grow faster than other isolates. They compared the isolate with two other clinical isolates (HN60 and HN878) and two laboratory strains (H37Rv and Erdman) ("Mycobacterium tuberculosis CDC1551 Induces a More Vigorous Host Response in vivo and in vitro, But is Not More...

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Source: TB and Outbreaks Week (1999-07-26)

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