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Sarcoidosis (Disease Association)

"Identification of Mycobacterial DNA in Cutaneous Lesions of Sarcoidosis."

Published in TB and Outbreaks Week, September 13th, 1999

According to the authors' abstract of an article published in Journal of Cutaneous Pathology, "Sarcoidosis is a multisystemic granulomatous disease of uncertain etiology. Recently, mycobacterial DNA, especially Mycobacterium tuberculosis and M. avium complex, were detected in lung tissue and bronchial lavage fluid from patients with sarcoidosis by polymerase chain reaction (PCR) assays in 30% to 50% cases. Moreover, cell wall-defective form (CWDF) acid-fast bacteria have been isolated from skin lesions of patients with sarcoidosis which were later confirmed as M. avium complex by PCR assays. CWDF acid-fast bacteria were also found to grow from the blood of 95%...

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