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Diagnostics (TB)

Multi-Antigen ELISA May Make Diagnosis Easier

Published in TB and Outbreaks Week, September 20th, 1999

A multi-antigen ELISA test could help simplify the diagnosis of tuberculosis.

The new serological assay (DETECT-TB, BioChem ImmunoSystems), uses three recombinant proteins and two synthetic peptides for the detection of the anti-Mycobacterium tuberculosis IgG. The test was evaluated by M. Amicosante and colleagues from Italy's University of Modena.

The researchers used a panel of serum specimens collected from 100 tuberculosis (TB) patients and 270 controls, in comparison with a homemade ELISA test using purified protein derivative (PPD) as antigen ("Sensitivity and Specificity of a Multi-Antigen ELISA Test for the Serological Diagnosis of...

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