TB Vaccine

M. tb Luciferase Reporter Tracks Vaccine Efficacy

Published in TB and Outbreaks Week, September 27th, 1999

The luciferase reporter strain of Mycobacterium tuberculosis may one day advance the assessment of tuberculosis vaccine efficacy.

"Measurement of luminescence is sensitive, stable, and simple to carry out, and a linear relationship generally exists between mycobacterial viability and bioluminescence in M. smegmatis, bacillus Calmette-Guerin (BCG), and M. tuberculosis," Valerie A. Snewin and colleagues wrote ("Assessment of Immunity to Mycobacterial Infection with Luciferase Reporter Constructs," Infection and Immunity, September 1999;67(9):4586-4593).

Protective immunity to mycobacterial infection is incompletely understood but...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of TB and Outbreaks Week

Source: TB and Outbreaks Week (1999-09-27)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry