TB Vaccines (Animal Models)

Mutant M. tuberculosis Evaluated for Immune Properties

Published in TB and Outbreaks Week, November 15th, 1999

A mutant of Mycobacterium tuberculosis deficient in antigen 85 complex B may prove to offer superior tuberculosis immunity, murine studies suggest.

The studies were presented at the First International Congress on Cytokines/Chemokines in Infectious Diseases, held September 8-10, 1999, in Bethesda, Maryland.

Bacillus Calmette-Guerin (BCG) vaccine has provided different levels of protection against tuberculosis ranging from 0-80 percent.

"The search for better vaccines has continued," C. Jagannath and colleagues from the University of Texas Health Science Center wrote in a poster presented at the conference.

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Source: TB and Outbreaks Week (1999-11-15)

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