Tuberculosis (Epidemiology)

Multidrug-Resistance Prevalent in Third-World Countries

Published in TB and Outbreaks Week, January 11th, 2000

Multidrug-resistant tuberculosis (MDR-TB) is defined as combined resistance to isoniazid and rifampicin. The disease is man-made and caused by improper treatment, inadequate drug supplies, or poor supervision of tuberculosis patients.

MDR-TB is often fatal, causes chronic disabilities, and is infectious. "Cure rates of 96 percent have been achieved but require prompt recognition of the disease, rapid accurate susceptibility results, and early administration of an individualized re-treatment regimen," according to I. Bastian and colleagues, Institute of Tropical Medicine, Belgium.

Treatment regimens are usually based on a quinolone and an injectable...

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Source: TB and Outbreaks Week (2000-01-11)

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