Published in TB and Outbreaks Week, January 18th, 2000
Serology is used routinely as an aid for diagnosing Lyme borreliosis, despite concerns about the sensitivity and specificity of many tests. The commercial release of the recombinant OspA vaccine for preventing Lyme disease will present additional problems for laboratory-based testing, noted Paul T. Fawcett and colleagues.
Reported efficacy of the vaccine, especially during the first year, indicates that a substantial number of vaccine recipients may become infected with Borrelia burgdorferi. The conventional enzyme-linked...
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