Herpes Simplex Virus

Elevated Dendritic Cells Enhance Viral Immunity

Published in TB and Outbreaks Week, February 1st, 2000

Elevated numbers of dendritic cells can produce enhanced protection against herpes simples virus type 1 (HSV-1), according to a report from England.

Previous research studies have demonstrated that Flt-3 ligand (Flt-3L) induces large numbers of lymphoid and myeloid dendritic cells (DC) in vivo, indicated Jo R. Smith and colleagues.

"We confirm that increasing doses of Flt-3L, administered subcutaneously to mice for 9 consecutive days, caused a corresponding increase in total spleen cell number," Smith et al. wrote in a study titled "Effect of Flt-3 ligand on HSV-1 pathogenesis," presented at the Joint Congress of the British Society for Immunology...

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Source: TB and Outbreaks Week (2000-02-01)

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