Published in TB and Outbreaks Week, February 1st, 2000
The M. leprae LSR (12 kDa) protein antigen has been reported to mimic whole cell M. leprae in T-cell responses across the leprosy spectrum. In addition, B-cell responses to specific sequences within the LSR antigen have been shown to be associated with immunopathological responses in leprosy patients with erythema nodosum leprosum.
In this study, F. Oftung and colleagues from Norway's National Institute of Public Health applied the M. leprae LSR DNA sequence as query to...
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