Published in TB and Outbreaks Week, March 14th, 2000
Ricardo E. Tascon and associates from the National Institute for Medical Research conducted a study to help clarify the cellular basis for the induction of protective anti-mycobacterial CD4+ and CD8+ T-cell responses. Researchers explained that DCs are readily infected with Mycobacterium tuberculosis (Mtb) and are present in the airway epithelium and lung parenchyma.
"Immortalized DC lines are a good model to study the molecular mechanisms involved in the activation and presentation of bacterial...
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