Tuberculosis
HLA-Restricted Immune Response Relevant to Vaccine Design
Published in TB and Outbreaks Week, March 21st, 2000
"Identification of mycobacterial antigens that are recognized by CD4+ Th1 cells in HLA-nonrestricted manner or in association with multiple allelic products is required to develop universally effective vaccines against mycobacterial diseases," wrote A.S. Mustafa and colleagues, Kuwait University, Kuwait. "Our studies in this direction have shown that several recombinant mycobacterial antigens of cytosolic and culture filtrate origin are recognized by CD4+ Th1 cells."
Mustafa et al. published their study in...
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