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Drug Development

Nature Leads Scientists to New Antibiotic Strategy

Published in TB and Outbreaks Week, April 25th, 2000

By mimicking one of nature's own potent antimicrobial defenses, scientists may have found a new way to wage war on pathogenic bacteria.

In the April 6, 2000, issue of the British scientific journal Nature, a team of scientists from the University of Wisconsin-Madison report the design, synthesis, and evaluation of a new type of molecule that exhibits a wide spectrum of antimicrobial activity, including against two species of bacteria that are resistant to common antibiotic drugs.

The work is important because it demonstrates the feasibility of developing a new class of antibiotics that can potentially overcome the growing resistance of...

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