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Tuberculosis

U.S.-Born Cases Generate More Secondary Cases than Immigrants

Published in TB and Outbreaks Week, May 30th, 2000

In a recent study, researchers from The Netherlands reported secondary cases of tuberculosis were generated more often by U.S.-born TB cases than immigrant cases.

"Restriction fragment length polymorphism (RFLP) typing was performed on Mycobacterium tuberculosis isolates from culture-positive pulmonary tuberculosis patients in San Francisco [California] (1991 through 1996), using IS6110 as a probe," explained M.W. Borgdorff and colleagues from Royal Netherlands TB Association.

Researchers assigned patients to clusters determined by isolates with identical DNA fingerprints and assumed the clusters to be caused by recent transmission.

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