Drug Resistance

Scientists Have New Approach to Combating Antibiotic Resistance

Published in TB and Outbreaks Week, June 27th, 2000

Researchers are focusing on aminoglycosides, a family of antibiotics that includes drugs such as neomycin, as a new tool to address the growing problem of antibiotic resistance.

The research was reported in the May 31 edition of the Journal of the American Chemical Society.

This class of antibiotics faces threats from its inherent high toxicity and its susceptibility to chemical modifications that allow bacteria to resist the drug's effects.

Bacteria, which create the proteins they need to survive, are constantly evolving and mutating in ways that circumvent the activity of antibiotics. To get around this problem, the...

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Source: TB and Outbreaks Week (2000-06-27)

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