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Immunization

Bacterial Components May Cause Allergic Reactions in Some Children

Published in TB and Outbreaks Week, August 29th, 2000

High doses of bacterial components may cause allergic reactions in some children, researchers note.

"We studied 27 children with suspected allergy to multivalent vaccines: pricks (undiluted) and intradermal (dilution 1/100) were performed with the multivalent and monovalent vaccines (diphtheria (D) tetanus toxoids (T) pertussis (P) polio (Pol) [DTPPol], DTP, DTPol, DT, and T and were assessed at 20 minutes (immediate) and eight hours (semi-late)," reported C. Ponvert and colleagues from the Sick Children's Hospital, France. "Specific immunoglobulin E (IgE) (CAP-RAST to T and formaldehyde) and immunoglobulin G (IgG) (D, T, Pol) were assessed in most children. ...

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