Immunology

Fatty Acids Influence Macrophage Activity Against Mycobacterium tuberculosis

Published in TB and Outbreaks Week, September 19th, 2000

Free fatty acids work in concert with substances called reactive nitrogen intermediates to influence the action of macrophages against Mycobacterium tuberculosis, according to researchers in Japan.

Medical investigators at Shimane Medical University studied the role of free fatty acids and their reactions with both reactive oxygen intermediates (ROI) and reactive nitrogen intermediates (RNI) in their influence on the antimicrobial activity of macrophages. RNI and ROI are antimicrobial effectors.

They used any of four growth accelerants to treat M. tuberculosis infected macrophages: quinacrine, arachidonyl trifuloromethylketone,...

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Source: TB and Outbreaks Week (2000-09-19)

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