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African Trypanosomiasis

Cytokines Play Vital Role in Etiology

Published in TB and Outbreaks Week, September 26th, 2000

Levels of cytokines, proteins used by the body as signalling devices, are correlated with the severity of several infectious diseases, including African trypanomiasis, researchers report.

A. Sharafeldin and colleagues with the Karolinska Institute in Sweden conducted a study to "evaluate the early induction of five potential cytokines in the central nervous system (CNS) and spleens from Trypanosoma brucei brucei (T. b. brucei)-inoculated and uninfected control Sprague-Dawley rats."

They reported their findings in a presentation titled "Cytokine profiles in the central nervous system and the spleen during the early course of experimental...

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