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Disease Associations

HIV-1 Infection Increases Risk of Malaria

Published in TB and Outbreaks Week, October 3rd, 2000

People in developing countries with HIV-1 infection may be twice as likely to develop malarial infection and disease compared with HIV-1 negative individuals, according to research published in the September 23, 2000, issue of The Lancet.

An association between HIV-1 and malaria is expected in theory, but has not been convincingly shown in practice. James Whitworth and colleagues at the Uganda Virus Research Centre studied the effects of HIV-1 infection and advancing immunosuppression on malaria infection and disease. HIV-1 positive and HIV-1 negative adults selected from a population in rural Uganda attended a clinic every three months (routine visits), and...

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