Drug Resistance
Mutations on Mycobacterium tuberculosis are Indicators for Rifampin Failure
Published in TB and Outbreaks Week, October 31st, 2000
That mutation was recently identified by researchers in a report in the International Journal of Tuberculosis and Lung Disease.
Mycobacterium tuberculosis isolates from a prison population in Madrid (n=29) and also from the general population in Spain (n=14) were characterized with gene sequencing analysis and IS6110 DNA fingerprinting.
Investigators specifically looked at the 81 bp (base-pair) core region of the rpoB gene for changes that would indicate mutation.
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