Malaria
Synthetic Long Peptide Elicits Protection Against Parasite
Published in TB and Outbreaks Week, November 7th, 2000
"We compared the immunogenicity of two preparations of a peptide derived from the Plasmodium berghei circumsporozoite protein, which is expressed on the surface of the preerythrocytic stage of the malaria parasite (PbCS242-310)," stated Vincent Brossard and colleagues from the Institute of Biochemistry, Epalinges. "The peptide was synthesized using a Fmoc/tBu solid phase strategy with a HOBT/DIPC activation, cleaved with the Barany's emulsion, precipitated in ether, purified by RP-HPCL, and folded."
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