Tuberculosis

Cytokines and T Helper Cells Ebb and Flow During Infection

Published in TB and Outbreaks Week, January 9th, 2001

New research indicates that cytokine and T-helper cell responses change during tuberculosis infection. Understanding those changes could be beneficial for developing new TB therapies, say authors of the new study.

The researchers monitored 34 pulmonary tuberculosis patients for changes in cytokine as well as T helper cell status during the nine-month study. Patients were evaluated prior to study initiation and then every three months after they began anti-tuberculosis therapy.

"Before the anti-TB chemotherapy the prevalent cytokine pattern was Th1, with a sensible increase of interleukin (IL)-2, soluble IL-2 receptor (sIL-2R), IL-12, gamma...

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Source: TB and Outbreaks Week (2001-01-09)

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