Published in TB and Outbreaks Week, February 13th, 2001
"Auxotrophic mutants of M. tuberculosis have been proposed as new vaccine candidates," wrote Debbie A. Smith and colleagues from the London School of Hygiene and Tropical Medicine. "We have analyzed the virulence and vaccine potential of M. tuberculosis strains containing defined mutations in genes involved in methionine (metB), proline (proC), or tryptophan (trpD) amino acid biosynthesis."
Smith et al....
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