Mycobacterium tuberculosis

Lab Strain H37Rv and Clinical Isolate CDC 1551 Maintain Similar Traits

Published in TB and Outbreaks Week, February 20th, 2001

by Michelle Marble, staff medical writer -- According to a study from England, two strains of Mycobacterium tuberculosis have maintained genomic similarities although they come from different environments.

"The genome sequences of two virulent strains of Mycobacterium tuberculosis (H37Rv and CDC 1551) are now available," wrote J.C. Betts and colleagues, Glaxo Wellcome Research & Development, Ltd. "CDC 1551 is a recent clinical isolate and H37Rv is a commonly used lab strain, which has been subject to in vitro passage. The two strains have been shown to display differing phenotypes both in vivo and in vitro."

"The proteomes of the two...

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Source: TB and Outbreaks Week (2001-02-20)

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