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Influenza

GS4104 Is Efficacious Against Zoonotic Avian Viruses

Published in TB and Outbreaks Week, March 6th, 2001

by Michelle Marble, staff medical writer -- The neuraminidase inhibitor GS4104 showed promising results when tested against avian influenza viruses, researchers in the United States report.

"In 1997, an H5N1 avian influenza A/Hong Kong/156/97 virus [was] transmitted directly to humans and killed six of the 18 people infected," said I.A. Leneva and colleagues, St. Jude Children's Research Hospital. "In 1999, another avian A/Hong/1074/99 (H9N2) virus caused influenza in two children. In such cases in which vaccines are unavailable, antiviral drugs are crucial for prophylaxis and therapy."

In search of those new antiviral agents, the Leneva team...

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