Dysentery

Researchers In Italy Develop Safe, Effective Shigella Vaccine

Published in TB and Outbreaks Week, March 20th, 2001

by N.R. Saltmarsh, staff medical writer -- Vaccination against Shigella spp. offers promise for protection against dysentery, and now researchers working in Italy have pinpointed one vaccine that appears safe and effective.

M.L. Bernardini and colleagues set out to find the strain of Shigella that was likely to offer the most protection, and to define parameters such as ideal route of administration and whether disease protection corresponded to antibody response in plasma. Their results were published in Infection and Immunity.

The researchers inoculated guinea pigs intranasally with three strains of Shigella flexneri: ...

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Source: TB and Outbreaks Week (2001-03-20)

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