Immunization

DTPa/Hib Single Injection Safer Than DTPw Plus Hib Given Separately

Published in TB and Outbreaks Week, April 3rd, 2001

by N.R. Saltmarsh, staff medical writer - A single injection of diphtheria-tetanus-acellular pertussis (DTPa) and Haemophilus influenzae type b conjugate (Hib) vaccine causes fewer local and systemic reactions than diphtheria-tetanus-whole cell pertussis (DTPw) and Hib vaccines given separately, say researchers working in Spain.

J. Aristegui and colleagues evaluated the safety profiles of the two vaccine delivery approaches in 18-month-old children previously given three doses of DTPw and Hib vaccines.

"Children were randomized to receive DTPa/Hib (group 1; n=111) or DTPw + Hib (group 2; n=105) and were followed for up to 30 days...

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Source: TB and Outbreaks Week (2001-04-03)

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