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Malaria

Development Of New Drugs Urged As Chloroquine Resistance Grows In Africa

Published in TB and Outbreaks Week, April 17th, 2001

by N.R. Saltmarsh, staff medical writer - Resistance of Plasmodium falciparum to chloroquine has rendered the drug next to useless in some areas of sub-Saharan Africa, and may even be responsible for emerging epidemics and mortality.

The limited supply of alternative anti-malarials highlights a need for development of more effective and plentiful drugs in African nations, said Fred Nuwaha at Mbarara University in Uganda.

"There is emerging evidence that chloroquine-resistant P. falciparum (CRPF) is linked with increased incidence of mortality, severe disease and emergence of epidemics," Nuwaha said. "Whereas the normal response to this...

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