Vaccine Development

Measurement Of Antibody-Secreting Cells Can Predict Effectiveness Of E. coli Vaccine

Published in TB and Outbreaks Week, May 15th, 2001

by N.R. Saltmarsh, staff medical writer - Circulating immunoglobulin A (IgA) antibody-secreting cells (ASCs) can be a good indication of how well a vaccine against Escherichia coli will work, say microbiologists.

M. Jertborn and colleagues at Gothenburg University, Sweden, studied the immunogenicity of different preparations of an oral inactivated enterotoxigenic E. coli (ETEC) vaccine consisting of recombinant cholera toxin B (CTB) subunit and various amounts of formalin-killed whole bacteria expressing the most prevalent colonization factor antigens (CFAs).

The majority of Swedish volunteers, who had not been previously exposed to...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of TB and Outbreaks Week

Source: TB and Outbreaks Week (2001-05-15)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry