Typhoid Fever

Youngest Children Have Greatest Disease Burden In Bangladesh

Published in TB and Outbreaks Week, June 19th, 2001

by N.R. Saltmarsh, staff medical writer - Contrary to current recommendations, development of a vaccine against typhoid fever should target the youngest children, say researchers working in a highly endemic area of Bangladesh.

S.K. Saha and associates found that infants and young children there were most likely to be affected by typhoid and that bacterial burden was inversely proportional to age.

In their prospective study of patients presenting to a large private diagnostic center in Bangladesh over a 16-month period, they identified 538 bacterial pathogens in 4,650 blood samples, of which 72.7% were Salmonella typhi, for a total incidence of...

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Source: TB and Outbreaks Week (2001-06-19)

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