Pseudomonas aeruginosa

Mouse Survival Prolonged With Dendritic Cell Vaccine

Published in TB and Outbreaks Week, July 3rd, 2001

by N.R. Saltmarsh, staff medical writer - Mice immunized with Pseudomonas aeruginosa-pulsed dendritic cells (DC) survive significantly longer after pulmonary infection with P. aeruginosa than unimmunized mice, according to a new study in Infection and Immunity.

"To develop a Pseudomonas aeruginosa vaccine that allows the host immune system to select the antigens, we hypothesized that dendritic cells (DC) pulsed with P. aeruginosa would induce protective immunity against pulmonary infections with P. aeruginosa," said S. Worgall and colleagues at Cornell University's Weill Medical College, New York.

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Source: TB and Outbreaks Week (2001-07-03)

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