Tuberculosis

Researchers Identify Critical Regulatory Gene

Published in TB and Outbreaks Week, July 24th, 2001

Controlling a tuberculosis infection requires an interplay of a distinct set of genes and immune system cells. Researchers are showing for the first time that the absence of one of those genes, called CCR2, can have fatal consequences.

Without CCR2, which encodes a receptor known to be important in the body's response to inflammation, containing a tuberculosis infection becomes impossible.

The study is a joint collaboration between the Gladstone Institute of Cardiovascular Disease and the University of California, San Francisco, Division of Infectious Diseases. A paper detailing the findings was published in the July 3, 2001, issue of the...

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Source: TB and Outbreaks Week (2001-07-24)

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