Lyme Disease

IL-6 Enhances Anti-B. burgdorferi Antibody Production

Published in TB and Outbreaks Week, September 4th, 2001

by N.R. Saltmarsh, staff medical writer - Interleukin-6 (IL-6) has a previously unrecognized role in the protective response against Borrelia burgdorferi, the pathogen responsible for Lyme disease, researchers in the United States have found.

The findings of M.C. Remington and colleagues, published in Infection and Immunity may have implications for vaccine development.

"We investigated the borreliacidal antibody response in sera and the amount of antibody produced by cultured lymph node cells of C3H/HeJ mice vaccinated with outer surface protein C (OspC)," reported Remington and coworkers. They noted that potent borreliacidal activity...

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Source: TB and Outbreaks Week (2001-09-04)

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