Published in TB and Outbreaks Week, November 6th, 2001
"Mycobacterium tuberculosis alone induces small, donor-variable amounts of tumor necrosis factor (alpha) (TNF-(alpha)) from primary human monocytes in vitro," explained Jan Warwick-Davies and colleagues at St. George's Hospital Medical School in London.
The addition of activated T-cells or their isolated membranes to such cultures triggered a huge increase in cytokine output, according to Warwick-Davies and coauthors.
Fixed, activated T cells (FAT) induced...
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