Drug Development
Inbuilt Antibiotics Inspire Drug Design
Published in TB and Outbreaks Week, February 5th, 2002
A recently published review article by Michael Zasloff of the University of Pennsylvania School of Medicine, Philadelphia, explained how it all works.
Zasloff rounded up the latest findings on the protein fragments that many multicellular organisms use to fend off bacteria, fungi, viruses, and protozoa. These peptides seem to have served a fundamental role in the successful evolution of complex life.
Little resistance seems to have arisen against these natural antimicrobials. As such, researchers are borrowing ideas and mechanisms from these proteins to...
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