AIDS And HIV Tuberculosis
Rifampicin Reduces Nevirapine Levels In Coinfected Patients
Published in TB and Outbreaks Week, February 12th, 2002
Dr. Esteban Ribera and colleagues at the Autonomous University of Barcelona's Hospital Vall d'Hebron examined the pharmacokinetics of the two drugs in patients with HIV related tuberculosis.
Rifampicin significantly lowers peak nevirapine concentrations in these patients although the clinical relevance of this effect may be limited, Ribera and coworkers said.
The researchers used high-performance liquid chromatography to determine levels of the two drugs in a...
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