Published in TB and Outbreaks Week, February 19th, 2002
One of the challenges posed by the tubercle bacillus is to understand how the bacillus, once it infects tissue, persists for a person's entire lifetime despite the attack of the body's immune system. Mycobacterium tuberculosis persists despite prolonged oxidative and nitrosative stress - forces that the immune system uses to kill many other invading pathogens.
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