Ebola Virus

Lipid rafts needed for intercellular viral transport

Published in TB and Outbreaks Week, April 16th, 2002

by Michael Greer, senior medical writer - Researchers in the United States have identified a key structure used by filoviruses - including the Ebola and Marburg viruses - for cellular transport.

"Spatiotemporal aspects of filovirus entry and release are poorly understood," explained Dr. Sina Bavari and colleagues at the U.S. Army Medical Research Institute of Infectious Diseases and Clinical Research Management Inc. in Frederick, Maryland. "Lipid rafts act as functional platforms for multiple cellular signaling and trafficking processes."

Filoviruses make extensive use of lipid rafts during cell invasion and cell egress, and during the generation of...

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Source: TB and Outbreaks Week (2002-04-16)

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