Microbiology

Novel peptide in saliva kills broad range of fungi and bacteria

Published in TB and Outbreaks Week, May 14th, 2002

A small piece of protein from one end of a larger molecule found in human saliva has been shown in laboratory tests to have potent antimicrobial activity against several types of bacteria and fungi, some of which are resistant to current drugs.

If these findings hold up in animal and human trials, the peptide, labeled MUC7 20-mer, could form the basis for promising new drugs for treating a wide range of infections, said Libuse Bobek, PhD, associate professor of oral biology in the University at Buffalo (UB) School of Dental Medicine and senior scientist on the research.

Results of the research were presented at the 2002 International Association of...

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Source: TB and Outbreaks Week (2002-05-14)

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