Tuberculosis Screening

Nitrate reductase assay is low-cost alternative to for drug resistance testing

Published in TB and Outbreaks Week, May 14th, 2002

by Michael Greer, senior medical writer - A novel assay that measures the activity of a key Mycobacterium tuberculosis enzyme may provide a low-cost alternative for drug susceptibility testsing, researchers in Sweden say.

"Multidrug-resistant tuberculosis is an increasing public health concern in many parts of the world, especially in low-income countries where most cases occur," explained Dr. Kristian Angeby and colleagues at the Swedish Institute for Infectious Disease Control in Solna and the Karolinska Institute in Stockholm. "Traditional drug susceptibility testing is either time consuming, such as the proportion method on solid media, or expensive, such as...

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Source: TB and Outbreaks Week (2002-05-14)

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