Tuberculosis Pathogenesis
Vascular endothelial growth factor produced by T cells in response to infection
Published in TB and Outbreaks Week, July 9th, 2002
Dr. Wataru Matsuyama and colleagues at Kagoshima University School of Medicine in Kagoshima and Ariake Medical Association Hospital in Ariake-cho Noikura conducted a study to "investigate the cellular source and significance of vascular endothelial growth factor (VEGF) which, as reported previously, is elevated in the sera of pulmonary tuberculous patients."
Tuberculosis-induced VEGF production appears to be part of an immune response by CD4+ T cells, Matsuyams and coauthors found.
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