Tuberculosis Therapy
Salicylate agents impair antimicrobial drug efficacy
Published in TB and Outbreaks Week, September 3rd, 2002
"Salicylate induces multiple antibiotic resistance in various bacterial species," according to Dr. Alain Schaller and colleagues working at Johns Hopkins University's Bloomberg School of Public Health in Baltimore.
Schaller and coauthors showed that salicylate-based drugs reduce M. tuberculosis susceptibility to a number of anti-TB medications.
The researchers used tetrazolium redox dye viability and bacterial survival assays to...
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