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Infectious Disease

Cytomegalovirus DNA levels predict CMV disease after kidney transplants

Published in TB and Outbreaks Week, September 24th, 2002

by Michael Greer, senior medical writer - Molecular testing for cytomegalovirus (CMV) can help determine patients at risk of developing CMV disease after kidney transplantation, researchers in Norway report.

Halvor Rollag and colleagues working at the University of Oslo Hospital evaluated the prognostic value of three CMV blood tests for kidney transplant patients.

The quantitative DNA test provided the most useful results, Rollag and coauthors found.

The researchers compared a test for CMV's pp65 antigen in leukocytes with two molecular assays, a quantitative and a qualitative polymerase chain reaction (PCR) CMV plasma screen. A...

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