Published in TB and Outbreaks Week, November 26th, 2002
"Superantigens are microbial proteins that induce massive activation, proliferation, and cytokine production by CD4+ T cells via specific Vbeta elements on the TCR [T cell receptor]," explained Barbara A. Torres and colleagues working at the University of Florida in Gainesville.
These proteins can be used to augment CD4 cell-induced humoral activity against a number of microbial and viral antigens, Torres and coauthors found.
The researchers evaluated the effect of...
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