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Malaria

New study provides molecular-level understanding of common antimalarial drugs

Published in TB and Outbreaks Week, December 10th, 2002

TransForm Pharmaceuticals, Inc., has announced a new understanding of the connection between the physical chemistry and mechanism of action of quinoline-based drugs used to treat malaria.

These findings can be applied to further discovery and design of research that may overcome the problem of drug resistance that has developed to the malaria parasite.

The study, conducted in collaboration with the Weizmann Institute in Israel, and published in the November/December 2002 issue of Crystal Growth and Design, provides new insights on how a better understanding of the physical chemistry, associated with some diseases, can be used to develop new...

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