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Infectious Disease Therapy

Yeast adhesin analogs can prevent intestinal C. albicans infection

Published in TB and Outbreaks Week, January 7th, 2003

by Michael Greer, senior medical writer - Researchers in France have identified a novel method for preventing intestinal yeast infections.

"The pathogenic yeast Candida albicans displays at its cell surface beta-1,2 oligomannosides (beta-1,2-Mans)," explained Francoise Dromer and colleagues at the Pasteur Institute and Ecole Normale Superieure in Paris, the University of Lille Hospital Center in Lille, and the University of Angers in Angers.

Synthetic beta-1,2-Man analogs virtually abolished intestinal C. albicans colonization in animals, Dromer and coauthors found.

The researchers evaluated the effects of synthetic...

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